An endoscope system includes: an illumination unit configured to irradiate a visual field area with illumination light that produces return light from a specific substance a sensor unit having a two-dimensional surface on which a plurality of pixels is arranged for receiving the return light from the visual field area and photoelectrically converting the return light to generate electrical signals a reading unit configured to read out the electrical signals per a specified frame cycle a reset pulse generation unit configured to generate reset pulses for releasing electric charges accumulated in the plurality of pixels a reset pulse controller configured to adjust timing of generating the reset pulses such that a plurality of frame cycles is included in a period between generation of two consecutive reset pulses and an illumination controller configured to cause the illumination unit to emit the illumination light in each of the plurality of frame cycles.
