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SUSTAINED RELEASE FORMULATION
专利权人:
Ltd.;Shionogi & Co.
发明人:
Naoya MIZUTANI,Go KIMURA,Yukiko NISHINO,Satoshi SAKUMA
申请号:
US15112798
公开号:
US20160331688A1
申请日:
2015.01.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention is a sustained release formulation which is capable of controlling dissolution of a drug and of enduring peristaltic movement of the gastrointestinal tract. Specifically, the present invention is: a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and an alkali agent, wherein the alkali metal salt is a sodium salt or a potassium salt, and the alkali agent is a magnesium oxide; or a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and a water soluble polymer or a hydrophobic base, wherein the alkali metal salt is a sodium salt or a potassium salt.
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