A method for assessing a liver includes acquiring image information including contrast-enhanced ultrasound images of the liver. A location of the main hepatic artery (MHA) and a location of the main portal vein (MPV) of the liver are identified in at least one of the contrast-enhanced ultrasound images of the liver. Time-intensity information corresponding to perfusion of a contrast agent in the MHA and the MPV is obtained. A biomarker index value (BW) which is a function of the time-intensity information corresponding to the perfusion of contrast agent in the MHA and the time-intensity information corresponding to the perfusion of contrast agent in the MPV is determined.