Colette Dezutter,Corinne Reymermier,Eric Perrier,Isabelle Orly,Sabine Pain,Valérie Andre
申请号:
BRPI0812575
公开号:
BRPI0812575B1
申请日:
2008.06.06
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The invention concerns active substances modulating the expression of the receptors of the products of the POMC gene (MC-1R, MC-2R, and the µ opioid receptor), and possibly modulating the expression of POMC in cutaneous cells, notably to modulate the proliferation and differentiation of epidermal cells in order to re-epithelial, maintain innervation, irrigate the skin, or restore normal pigmentation, or to fight against aging, or to modulate pigmentation independently or not of cutaneous aging. The invention also concerns a method of screening such active substances.