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PYRAZOLOQUINOLINE DERIVATIVE
专利权人:
.LTD;EISAI R &D MANAGEMENT CO
发明人:
NORIMINE,YOSHIHIKO,HAGIWARA KOJI,ISHIHARA,YUKI,TAKEDA,KUNITOSHI,SUZUKI,YUICHI,SATO,NOBUAKI
申请号:
ZA201402439
公开号:
ZA201402439B
申请日:
2014.04.02
申请国别(地区):
ZA
年份:
2015
代理人:
摘要:
A compound or pharmacologically acceptable salt thereof represented by the formula (I) has PDE9 inhibitory action, so that the intracerebral cGMP concentration is anticipated to be elevated. The PDE9 inhibitory action and the increase in cGMP lead to the improvement of learning and memory behaviors, and the compound (I) has a potential use of a therapeutic agent for cognitive dysfunctions in Alzheimer's disease. wherein R 1 is a hydrogen atom; R 2 is an aromatic ring group, etc.; R 3 is a hydrogen atom, etc; R 4 is a hydrogen atom; R 5 is an oxepanyl group, etc.; R 6 is a hydrogen atom.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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