您的位置: 首页 > 农业专利 > 详情页

Recombinant Ganodermalucidum immunoregulatory protein (rLZ-8) and uses thereof
专利权人:
シチャン・ツァン
发明人:
フェイ・サン,シチャン・ツァン
申请号:
JP2010541002
公开号:
JP5735280B2
申请日:
2008.12.30
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention relates to medical uses of a recombinant Ganoderma Lucidum Immunoregulatory Protein (rLZ-8) for anti-tumor, increase of the number of leucocyte and inhibiting immunological rejection, etc. The protein gene sequence was originated from Ganoderma Lucidum and redesigned such that it was more suitable for recombinant expression by eukaryote expression system of Pichia pastoris . Crystal structure (tertiary and quaternary structures) of rLZ-8 was obtained by X-ray diffraction, analysis was performed based on the combination of said crystal structure and relevant functions thereof, a conclusion was drawn that any protein molecule having said structure has the foresaid medical uses, this has already been verified by large number of in vivo and in vitro pharmacodynamic studies. In conclusion, the recombinant Ganoderma Lucidum Immunoregulatory Protein (rLZ-8) of the present invention can be used as an anti-tumor drug or a increase of the number of leukocyte drug or an immunoinhibitor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充