It there is described herein a kind of pharmaceutical composition for containing camptothecine as active constituent. It especially depicts and releases immediately treatment system with what raising 7- [(E)-tertiary fourth oxyimino group methyl] camptothecine oral absorption, it includes being made of liquid amphiphilic substance or the matrix of the fusing point with 60 °C of low what, active constituent is at least partly dissolved and/or disperses and/or inglobated wherein.在此描述了一種含有喜樹碱作爲活性成分的藥物組合物。特別是描述了用於提高7-[(E)-叔丁氧亞氨基甲基]喜樹碱口服吸收的立即釋放治療系統,其包含由液態兩親物質組成或具有低於60°C的熔點的基質,在其中活性成分至少部分溶解和/或分散和/或inglobated。