Won KIM,Sung Kwang PARK,Kyung Pyo KANG,Yu Jin JUNG
申请号:
US15129664
公开号:
US20170128459A1
申请日:
2014.05.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition containing a SIRT2 inhibitor and, more specifically, to: a pharmaceutical composition for preventing or treating renal inflammatory diseases, which are caused by sepsis, by controlling inflammation-inducing factors by sepsis through the regulation of SIRT2 gene expression so as to reduce renal inflammation, thereby preventing a kidney injury and a pharmaceutical composition for preventing or treating cancer, having an effect of increasing anticancer efficacy while reducing nephrotoxicity, which is a side effect of cisplatin, when administered together with cisplatin.