JAKOBOVITS, AYA,FOORD, ORIT,LIN, ANDY AN-DEH,SANTAGUIDA, MARIANNE THERESA
申请号：
CA2966634
公开号：
CA2966634A1
申请日:
2015.11.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to engineered ?d T-cell(s) and methods for using the same as a therapeutic with a potent and selective ability to target an antigen of choice. Engineered ?d T-cells of the disclosure are useful in the treatment of various cancers, infectious diseases, and immune disorders. Also disclosed are methods for expanding engineered and non-engineered ?d T-cell(s) populations to therapeutically useful quantities. An engineered ?d T-cell of the disclosure can be a universal donor, and can be administered to a subject with any MHC haplotype.
