Atul J. Shukla,Anthony Edward Soscia,Yingxu Peng,Yichun Sun,James R. Johnson
申请号:
US13692117
公开号:
US08507001B2
申请日:
2012.12.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A dosage form from which a burst release of a drug contained within a tampered dosage form is reduced or retarded by the presence in or on the dosage form of a TPTA (Tamper Prone Therapeutic Agent) trap. If the dosage form has not been tampered with, the TPTA trap does not significantly interfere with the rate of release of the drug from the dosage form. However, if the dosage form has been physically tampered with, the TPTA trap reduces or retards burst release of the drug from the dosage form.