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USE OF LAG-3 AS AN MHC CLASS II LIGAND IN COMBINATION WITH AN ANTIGEN FOR THE MANUFACTURE OF A MEDICAMENT FOR AMPLIFYING A CELL RESPONSE TO AN ANTIGEN
专利权人:
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;INSTITUT GUSTAVE ROUSSY;MERCK SERONO S.A.
发明人:
申请号:
IL13421200
公开号:
IL134212A
申请日:
2000.01.24
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
The present invention concerns a use of a MHC class II ligand, such as CD4 and LAG-3, for the manufacture of a medicament for preventing or treating pathological conditions involving an antigen specific immune response, as well as the use of LAG-3 in cancer-immunotherapy. The invention also concerns a pharmaceutical composition comprising an effective amount of an antigen able to induce an antigen-specific immune response together with an effective amount of MHC class II ligand wherein said MHC class II ligand is present as an adjuvant-like agent.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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