SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY

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专利权人:

BOEHRINGER INGELHEIM INT

发明人:

OOST THORSTEN,ANDERSKEWITZ RALF,GNAMM CHRISTIAN,HOESCH HOLGER,MORSCHHAEUSER GERD,PETERS STEFAN,RIES UWE JOERG

申请号：

AP2016009632

公开号：

AP2016009632A0

申请日:

2015.07.30

申请国别(地区):

AP

年份:

2016

代理人:

摘要：

This invention relates to substituted bicyclic dihydropyrimidinones of formula 1and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.

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中国工程科技知识中心

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