The present invention provides a selectively activatable patch-pump assembly, said patch- pump assembly comprising: • a sealed prefilled drug-reservoir containing a drug to be delivered • an associated conduit in connection therewith • a selectively activatable penetrator which penetrates said sealed prefilled drug-reservoir and facilitates drug access to said conduit and • a selectively activatable, associated, cannula-containing assembly for delivering a drug subcutaneously to a subject, in fluid connection with said conduit wherein a selective activation-step initiates penetration of said sealed prefilled drug-reservoir, drug access from said drug-reservoir to said conduit, drug access from said conduit to said cannula-containing assembly and delivery from said cannula-containing assembly, thereby being a selectively activatable patch-pump assembly.
