Rznomics Inc.;Industry-Academic Cooperation Foundation, Dankook University;Dong-A University Research Foundation for Industry Academy Cooperation
发明人:
Seong-Wook Lee,Chang Ho Lee,Seung Ryul I Han,Ji Hyun Kim,Eun Yi Cho,Jin Sook Jeong,Mi Ha Ju
申请号:
US16797663
公开号:
US20200270612A1
申请日:
2020.02.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A cancer-specific trans-splicing ribozyme and a use thereof are disclosed. The trans-splicing ribozyme does not act on normal tissue, but is specifically expressed in cancer tissue. Therefore, it is very safe and has excellent expression efficiency at the post-transcription level, and thus can be effectively used in treatment of cancer.