RÉTICULATION UV SÉLECTIVE DE PEPTIDES ET DE FRACTIONS FONCTIONNELLES AVEC DES IMMUNOGLOBULINES

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专利权人:

University Of Notre Dame Du Lac

发明人:

申请号：

EP14768752.9

公开号：

EP2970440A4

申请日:

2014.03.14

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

A method of crosslinking a hetero-bifunctional photo crosslinking compound to an immunoglobulin having at least one heterocyclic photo reactive group and at least one non-photo reactive group where the non-photo reactive group is coupled to an effector molecule and the photo reactive group is coupled to the nucleotide binding site of an immunoglobulin. Alternatively, the photo crosslinker contains an orthogonal reactive group such as a thiol, which can be coupled to an effector molecule or functionalized ligand.

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中国工程科技知识中心

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http://www.ckcest.cn/home/