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DRUG SUSTAINED-RELEASE CARRIER AND METHOD FOR PRODUCING SAME
专利权人:
COSMED PHARMACEUTICAL CO., LTD.;NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY
发明人:
Ying-shu Quan,Tooru Ooya,Rongrong Jiang,Fumio Kamiyama
申请号:
US16537191
公开号:
US20190358331A1
申请日:
2019.08.09
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A DDS carrier enabling sustained release of a drug and a production method therefor. Wherein, the drug is retained by a PEG-carboxy group-containing polymer graft. Among polymers, a carboxy group-containing polysaccharide can be suitably used. The PEG-carboxy group-containing polymer graft is a compound prepared by grafting PEG into the carboxy group-containing polysaccharide. When the carboxy group-containing polysaccharide is used, it can be produced by utilizing a condensation reaction of an aminated PEG and a carboxy group-containing polysaccharide in coexistence with a triazine-based condensing agent. Alternatively, the PEG-carboxy group-containing polysaccharide graft can be produced by utilizing a condensation reaction of PEG and a carboxy group-containing polysaccharide in coexistence with an acid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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