Michael O'Neil Hanrahan Clarke,Joy Yang Feng,Robert Jordan,Richard L. Mackman,Adrian S. Ray,Dustin Siegel
申请号:
US16265016
公开号:
US10695361B2
申请日:
2019.02.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I:wherein the 1′; position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.