Compounds particularly for use in an autoimmune inflammatory disease and especially the treatment of inflammatory bowel disease have the formula: wherein R is selected from one or more of the same or different of hydrogen, hydroxyl, optionally substituted alkyl, optionally substituted aryl, alkoxy, aryloxy, thiol, and optionally substituted amino, and wherein R1 is selected from one or more of the same or different of hydrogen, acetyl, optionally substituted alkyl, optionally substituted aryl, and an amino acid selected from leucine, valine, isoleucine, and glycine.本發明揭示特別用於自體免疫發炎疾病及尤其治療發炎性腸病之化合物，其具有下式：其中R係選自以下相同或不同之一者或多者：氫、羥基、視情況經取代之烷基、視情況經取代之芳基、烷氧基、芳氧基、硫醇，及視情況經取代之胺基，及其中R1係選自以下相同或不同之一者或多者：氫、乙醯基、視情況經取代之烷基、視情況經取代之芳基，及選自白胺酸、纈胺酸、異白胺酸及甘胺酸之胺基酸。
