The present invention relates to anti-GPC3 antibodies and their applications. The invention investigates the potential inhibitory effect of anti-GPC3 antibodies on tumor growth, proliferation, migration and their applications for diagnostic and therapeutic purposes.La présente invention concerne des anticorps anti-GPC3 et leurs applications. Linvention étudie leffet inhibiteur potentiel danticorps anti-GPC3 sur la croissance tumorale, la prolifération, la migration, et leurs applications à des fins diagnostiques et thérapeutiques.