The present invention relates to a production method for a hydroxyl-radical-generating composition and to a hydroxyl-radical-generating composition produced by means of the method. More specifically, the present invention relates to a production method for a hydroxyl-radical-generating composition whereby a hydroxyl radical can be generated naturally even without light irradiation or plasma, by coating a shell to which a transition metal compound has been attached onto the surface of a core to which a superoxide-generating compound has been attached, such that a hydroxyl radical is generated as the superoxide generated from the core passes through the shell to which the transition metal compound has been attached, and the present invention relates to a hydroxyl-radical-generating composition produced by means of the method.La présente invention concerne un procédé de production pour une composition de génération de radicaux hydroxyle et une composition de génération de radicaux hydroxyle produite au moyen du procédé. Plus précisément, la présente invention concerne un procédé de production pour une composition de génération de radicaux hydroxyle grâce à quoi un radical hydroxyle peut être généré naturellement même sans irradiation de lumière ou plasma, par revêtement dune écorce à laquelle un composé de métal de transition a été fixé sur la surface dun cœur auquel un composé de génération de superoxyde a été fixé, de telle sorte quun radical hydroxyle est généré alors que le superoxyde généré à partir du cœur passe à travers lécorce à laquelle le composé de métal de transition a été fixé, et la présente invention concerne une composition de génération de radicaux hydroxyle produite au moyen du procédé.본 발명은 하이드록시 라디칼 생성 조성물의 제조방법 및 이 방법에 의해 제조된 하이드록시 라디칼 생성 조성물에 관한 것으로, 더욱 상세하게는 전이금속화합물이 고착된 쉘을 슈퍼옥사이드를 생성하는 화합물이 고착된 코어의 표면에 코팅시켜, 상기 코어로부터 생성되는 슈퍼옥사이드가 전이금속화합물이 고착된 쉘을 통과하면서 하이드록시 라디칼을 생성하게 됨으로써, 광조사 또는 플라즈마 없이도 자연적으로 하이드록시 라디칼을 생성할 수 있도록 하는 하이드록시 라디칼 생성 조성물의 제조방법 및 이