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One-pot process for the synthesis of dalfampridine
专利权人:
Fabio Garavaglia
发明人:
Fabio Garavaglia,Alessandro Barozza,Jacopo Roletto,Paolo Paissoni
申请号:
US13154866
公开号:
US08877935B2
申请日:
2011.06.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A process for the preparation of Dalfampridine (1), 4-aminopyridine, starting from 4-pyridinecarbonitrile using a one-pot procedure.Said process is carried out with no need for isolating intermediates and is particularly advantageous as far as environment, yields, productivity and purity of the resulting product are concerned, both in the reaction mixture and in the isolated crystal.
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