Brodney, Michael Aaron,Davoren, Jennifer Elizabeth,Dounay, Amy Beth,Efremov, Ivan Viktorovich,Gray, David Lawrence Firman,Green, Michael Eric,Henderson, Jaclyn Louise,Lee, Chewah,Mente, Scot Richard,O
申请号:
HRP20191163
公开号:
HRP20191163T1
申请日:
2019.06.27
申请国别(地区):
HR
年份:
2019
代理人:
摘要:
The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), age-related cognitive decline, dementia, and Parkinson's disease.