benzodiazepine derivatives, compositions and methods for the treatment of cognitive impairment

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专利权人:

AGENEBIO; INC

发明人:

JOHN A. LOWE III

申请号：

BR112013012072

公开号：

BR112013012072A2

申请日:

2011.11.15

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those benzodiazepine derivatives and methods of using those derivatives or compositions in treating central nervous system (CNS) disorders with cognitive impairment that are responsive to agonists of alpha5 subunit containing GABAA receptor, e.g., age-related cognitive impairment, Mild Cognitive Impairment (MCI), dementia, Alzheimer's Disease (AD), prodromal AD, post traumatic stress disorder (PTSD), schizophrenia and cancer-therapy-related cognitive impairment.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/