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ANTI-CXCR4 ANTIBODIES AND CONJUGATES ANTIBODY MEDICINE
专利权人:
ПФАЙЗЕР ИНК. (US)
发明人:
ХО Вэй-Хсиен (US),ЛЮ Шу-Хуэй (US),ПЕРНАСЕТТИ Флавиа Мерсер (US)
申请号:
RU2016103157
公开号:
RU2016103157A
申请日:
2014.07.28
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
The present invention provides antibodies and related molecules that bind to chemokine receptor 4 (CXCR4). The invention further provides antibody-drug conjugates comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and anti-CXCR4 antibody-drug conjugates for the treatment of a disorder associated with CXCR4 function or expression (e.g., cancer), such as colon, RCC, esophageal, gastric, head and neck, lung, ovarian, pancreatic cancer or hematological cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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