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COMPOSITION OF DOCETAXEL LIPOSOMAL INJECTION WITH HIGH DRUG LOADING
专利权人:
SHILPA MEDICARE LIMITED
发明人:
KIRAN K JADHAV,PRASHANTH S,SHIVAKUMAR PRADEEP,SREENIVASA REDDY
申请号:
US16480308
公开号:
US20200281888A1
申请日:
2018.11.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a pharmaceutical liposomal composition comprising of about 0.8% w/w to about 1% w/w of docetaxel, about 30% w/w to about 38% w/w of Soya Phosphatidyl Choline, about 0.2% w/w to about 0.8% w/w of Sodium Cholesteryl Sulfate, about 61% w/w to about 68% w/w of Sucrose and a pH adjusting agent, wherein the pH of liposomal composition is less than 3.5 and the process for preparation thereof.
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