593312 Provided are monoclonal human antibodies or an antigen-binding fragments thereof specific for human Fas ligand protein (FasL), with specified amino acid sequences in the six CDRs, and antibodies or antigen-binding fragments thereof which recognize the same epitope on human FasL, when used for the manufacture of a medicament for the prevention and/or treatment of a skin disease associated with keratinocyte acantholysis.
