СЕЙЕР Джеффри Дж. (US),КОНДЕР Эми Л. (US),ТЕЙЛОР Энджела П. (US),ШОУ Бонни Рене (US)
申请号：
RU2011150661/15
公开号：
RU2011150661A
申请日:
2010.06.21
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A pharmaceutical composition comprising a core, wherein said core contains ibuprofen sodium and said composition has a low sodium content. The pharmaceutical composition according to claim 1 in the form of a tablet or caplet, further comprising at least one shell. A pharmaceutical composition comprising a core, wherein said core contains ibuprofen sodium and said composition has a ratio of ibuprofen sodium to a total sodium content of about 11: 1.4. A pharmaceutical composition comprising a coated core, wherein said core contains ibuprofen sodium, wherein said coated core has a sodium content of less than 23 mg / unit dose. The pharmaceutical composition according to any one of claims 2 to 4, wherein Tibuprofen for a person taking two such cores is about or less than 40 minutes. The pharmaceutical composition according to any one of claims 2 to 4, wherein the core further comprises at least one binder. A pharmaceutical composition according to any one of claims 2 to 4, wherein the core further comprises at least two binders. The pharmaceutical composition according to any one of claims 2 to 4, wherein the ibuprofen sodium in the tablet core is in the form of a dihydrate. The pharmaceutical composition of claim 8, wherein ibuprofen sodium dihydrate is present in an amount of 50 to 90% by weight based on the weight of the core of the pharmaceutical composition. The pharmaceutical composition of claim 8, wherein ibuprofen sodium dihydrate is present in an amount of 60 to 80% by weight based on the weight of the core of the pharmaceutical composition. The pharmaceutical composition of claim 8, where ibuprofen sodium hydrate is present in an amount of from 60 to 70% by weight based on the weight�1. Фармацевтическая композиция, содержащая ядро, где указанное ядро содержит ибупрофен натрия и указанная композиция имеет низкое содержание натрия.2. Фармацевтическая композиция по п.1 в форме таблетки или каплеты, дополнительно содержащая по меньшей мере одну оболочку.3. Фар
