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Method of treating acute myeloid leukemia and/or acute lymphoblastic leukemia using thienotriazolodiazepine compounds
专利权人:
Kay Noel;Oncoethix SA;Maria Riveiro
发明人:
Noel, Kay,Riveiro, Maria E.
申请号:
AU2015252844
公开号:
AU2015252844A1
申请日:
2015.05.01
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
A method of treating acute myeloid leukemia, acute lymphoblastic leukemia, high risk myelodysplastic syndrome, and/or HR-MDS/AML in a mammal by administering a solid dispersion comprising an amorphous thienotriazolodiazepine compound of the Formula (1) wherein R1 is alkyl having a carbon number of 1-4, R2 is a hydrogen atom; a halogen atom; or alkyl having a carbon number of 1-4 optionally substituted by a halogen atom or a hydroxyl group, R3 is a halogen atom; phenyl optionally substituted by a halogen atom, alkyl having a carbon number of 1-4, alkoxy having a carbon number of 1-4 or cyano; -NR 5 -(CH 2)m R6 wherein R5 is a hydrogen atom or alkyl having a carbon number of 1-4, m is an integer of 0-4, and R6 is phenyl or pyridyl optionally substituted by a halogen atom.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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