BUGGY, Joseph, J.,ELIAS, Laurence,FYFE, Gwen,HEDRICK, Eric,LOURY, David, J.,MODY, Tarak, D.
申请号:
USUS2011/039190
公开号:
WO2011/153514A9
申请日:
2011.06.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.