DYKE, HAZEL JOAN,ELLWOOD, CHARLES,GANCIA, EMANUELA,GAZZARD, LEWIS J.,GOODACRE, SIMON CHARLES,KINTZ, SAMUEL S.,LYSSIKATOS, JOSEPH P.,MACLEOD, CALUM,WILLIAMS, KAREN,CHEN, HUIFEN
申请号：
CA2725754
公开号：
CA2725754C
申请日:
2009.06.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a)and (I-b) which are useful as kinaseinhibitors, more specifically useful as checkpoint kinase 1(chkl) inhibitors,thus useful as cancer therapeutics. The invention alsorelates to compositions, more specifically pharmaceutical compositionscomprising these compounds and methods of using thesame to treat various forms of cancer and hyperproliferative disorders, aswell as methods of using the compounds for in vitro, insitu, and in vivo diagnosis or treatment of mammalian cells, or associatedpathological conditions.
