The use of bio-printers in regenerative medicine used in recent years for these purposes. The basic problems of these inventions are the lack of mechanical strength in the absence of complete processes for the injection of different materials with distinct cells, the lack of stabilization of the biological substance (bio ink) and low uniform cell distribution. The solution is production of a new portable augmentative device incorporates precise control mechanisms with the isolated chamber with hybrid bioprinting system for the production of soft and hard tissue with the morphology of the organ. With structural modification mechanism of the low power laser an plasma also incresea compatibility of polymers and increasing cell adhesion and integration in the scaffolds.