Massachusetts Institute of Technology;Versitech Limited
发明人:
Rutledge Ellis-Behnke,Yu-Xiang Liang,Gerald E. Schneider,Kwok-Fai So,David K. C. Tay
申请号:
US15341949
公开号:
US10137166B2
申请日:
2016.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. In one embodiment, the formulation is provided as a dry or lyophilized powder. In another embodiment, the material is provided in water. In another embodiment, the material is provided in combination with an oil and forms a laminate.