An administration device includes a container body which defines therein a chamber containing at least two substances to be administered in at least two distinct, not spontaneously emulsifiable states a permeable fragmentation diaphragm which divides the containing chamber into a first half-chamber in which substances to be administered are loaded and a contiguous second half-chamber in which the at least two substances to be administered are mixed a thrust member pushing at least one of the at least two substances to be administered from the first half-chamber into second half-chamber through the permeable diaphragm and pushing the at least two substances after emulsification from the second semi-chamber into a recipient and an outlet from the second half-chamber to the recipient.