Method and composition for drug discovery, it is characterised in that the analysis of a proliferative disorder of the abnormal cell in a mammalian subject and processing according to include one pharmaceutically its combination of effective dose of management it is of the invention in terms of offer: a cytotoxic agent, one combine excitant and a kind of combination ribosome antagonist. The corresponding aspect of method and composition of the invention adjusts agent effective and/or influences the conversion insertion of selection it is characterized in that in Anomalous Diffusion, such as the cell of a cancer cell, therefore promotes the death of cell.