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Piperidinyl naphthylacetic acids
专利权人:
Hoffman-La Roche Inc.
发明人:
Fariborz Firooznia,Tai-An Lin,Eric Mertz,Achyutharao Sidduri,Sung-Sau So,Jefferson Wright Tilley
申请号:
US13706497
公开号:
US08691993B2
申请日:
2012.12.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention is concerned with the compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
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