FIROOZNIA, FARIBORZ,LIN, TAI-AN,MERTZ, ERIC,SIDDURI, ACHYUTHARAO,SO, SUNG-SAU,TILLEY, JEFFERSON WRIGHT
申请号:
CA2855940
公开号:
CA2855940A1
申请日:
2012.12.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.