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Aryl isoxazole compounds with antitumoural activities
专利权人:
Silvia Carminati;Giuseppe Paolo Carminati;Walter Cabri;Giuseppe Giannini;Daniele Simoni;Riccardo Baruchello;Claudio Pisano;Gabriella Singrossi
发明人:
Giuseppe Giannini,Walter Cabri,Daniele Simoni,Riccardo Baruchello,Paolo Carminati,Claudio Pisano
申请号:
US13001652
公开号:
US08383616B2
申请日:
2009.06.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to formula I compounds having antitumoural activities through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical compositions containing such compounds.
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