GIANNINI, GIUSEPPE,CABRI, WALTER,VESCI, LOREDANA,PISANO, CLAUDIO,CERVONI, MARIA LUISA,TADDEI, MAURIZIO,FERRINI, SERENA
申请号:
TW100146814
公开号:
TW201249814A
申请日:
2011.12.16
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention relates to aryl triazole derivatives of Formula I having antitumoural activity through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical composition containing such compounds.