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PROCÉDÉ DE PRODUCTION D'UN COMPOSÉ AMIDE DE L'ACIDE BENZOÏQUE À SUBSTITUTION ISOXAZOLINE
专利权人:
NISSAN CHEMICAL INDUSTRIES; LTD.
发明人:
申请号:
EP09794492.0
公开号:
EP2308857B1
申请日:
2009.07.09
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
[Problem] To provide a production method of an isoxazoline-substituted benzoic acid amide compound. [means for solving the problem] A production method of an isoxazoline-substituted benzoic acid amide compound of Formula (1) where X is a halogen atom, C 1-6 haloalkyl, etc., Y is a halogen atom, C 1-6 alkyl, etc., R 1 is a C 1-6 haloalkyl, etc., R 2 and R 3 independently of each other are a hydrogen atom, C 1-6 alkyl, etc., R 4 is C 1-6 alkyl, C 1-6 haloalkyl, etc., R 5 is a hydrogen atom, C 1-6 alkyl, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, comprising: reacting an isoxazoline-substituted benzene compound of Formula (3) where X, Y, R 1 , m, and n are the same as defined above, L is a chlorine atom, a bromine atom, -C(O)OH, -C(O)J, etc., J is a halogen atom, with a 2-aminoacetic acid amide compound of Formula (2) where R 2 , R 3 , R 4 , and R 5 are the same as defined above, or a salt thereof; crystal forms and the production method thereof
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