The present invention relates to protein-inhibitorysubstituted pyrrolopyridine derivatives of formula (I) in which X, Y, R1,R2, R3 and R4 are as defined herein, to pharmaceutical compositionsand combinations comprising the compounds according to theinvention, and to the prophylactic and therapeutic use of the inventivecompounds, respectively to the use of said compounds for manufacturingpharmaceutical compositions for the treatment or prophylaxis ofdiseases, in particular for neoplastic disorders, repectively cancer orconditions with dysregulated immune responses or other disordersassociated with aberrant MAP4K1 signaling, as a sole agent or in combina-tion with other active ingredients. The present invention further relatesto the use, respectively to the use of said compounds for manufacturingpharmaceutical compositions for the treatment or prophylaxis ofprotein inhibitors in benign hyperplasias, atherosclerotic disorders, sepsis,autoimmune disorders, vascular disorders, viral infections, inneurodegenerative disorders, in inflammatory disorders, in atheroscleroticdisorders and in male fertility control.
