THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;THE UNIVERSITY OF QUEENSLAND
发明人:
AVRIL ROBERTSON,KATE SCHRODER,LUKE O'NEILL,MATT COOPER,REBECCA COLL
申请号：
BR112017017610
公开号：
BR112017017610A2
申请日:
2016.02.16
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
These are certain sulphonylureas and related compounds which have advantageous properties and show useful activity in inhibiting activation of inflammasome nlrp3. Such compounds are useful in treating a wide variety of disorders in which the inflammation process, or more specifically, the inflammasome nr3, has been recognized as a key factor.trata-se de determinadas sulfonilureias e compostos relacionados que têm propriedades vantajosas e mostram atividade útil na inibição de ativação do inflamassoma nlrp3. tais compostos são úteis no tratamento de uma ampla variedade de distúrbios nos quais o processo de inflamação ou, mais especificamente, o inflamassoma nlrp3, foi reconhecido como um fator-chave.
