SELECTIVE INHIBITORS OF alpha2 ISOFORM OF Na,K-ATPase AND USE FOR REDUCTION OF INTRA-OCULAR PRESSURE

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专利权人:

发明人:

申请号：

EP14839412.5

公开号：

EP3039030A4

申请日:

2014.08.27

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention relates to digoxin and digitoxin derivatives that are selective inhibitors of the α2 isoform of Na,K-ATPase, and that reduce intra-ocular pressure. The invention further relates to uses of these derivatives for treating disorders associated with elevated intraocular pressure, such as glaucomas, and/or as cardiotonic agents.

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