Steven J.D. KARLISH;Daniel M. TAL;MARCOVICH ARIE;Adriana KATZ;YEDA RESEARCH AND DEVELOPMENT CO. LTD.
发明人:
Steven J.D. KARLISH,Adriana KATZ,Daniel M. TAL,MARCOVICH ARIE
申请号:
IL24435916
公开号:
IL244359A
申请日:
2016.02.29
申请国别(地区):
IL
年份:
2019
代理人:
摘要:
The present invention relates to digoxin and digitoxin derivatives that are selective inhibitors of the Alpha2 isoform of Na,K-ATPase, and that reduce intra-ocular pressure. The invention further relates to uses of these derivatives for treating disorders associated with elevated intraocular pressure, such as glaucomas, and/or as cardiotonic agents.