Refers to a topical Pharmaceutical composition comprising: a) a cyclic depsipeptide of formula (ii) (b) a Hydrophobic Matrix that includes one or more compounds selected from paraffins, vegetable oils, animal Fats, Synthetic Glycerides, among others and (c) an agent of consis Companies such as Isopropyl Myristate.Said composition also comprises one or more excipients selected from antioxidants, Gelling agents, regulators, Conservative, among others. The composition is useful for the treatment of inflammatory diseases and \/ or hyperproliferative and pruritic SkinSE REFIERE A UNA COMPOSICION FARMACEUTICA TOPICA QUE COMPRENDE: A) UN DEPSIPEPTIDO CICLICO DE FORMULA (II) B) UNA MATRIZ HIDROFOBICA QUE INCLUYE UNO O MAS COMPUESTOS SELECCIONADO A PARTIR DE PARAFINAS, ACEITES VEGETALES, GRASAS ANIMALES, GLICERIDOS SINTETICOS, ENTRE OTROS Y C) UN AGENTE DE CONSISTENCIA TAL COMO MIRISTATO DE ISOPROPILO. DICHA COMPOSICION ADEMAS COMPRENDE UNO O MAS EXCIPIENTES SELECCIONADOS DE ANTIOXIDANTES, AGENTES GELIFICANTES, REGULADORES, CONSERVADORES, ENTRE OTROS. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS Y/O HIPERPROLIFERATIVAS Y PRURITICAS DE LA PIEL
