BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
发明人:
DAVID, AYELET,ASHKENASY, GONEN,SHAMAY, YOSSI
申请号：
EP11789344
公开号：
EP2575848A4
申请日:
2011.05.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The caged cell-penetrating peptide (cCPP) conjugates of this invention are ideal for intracellular delivery of a broad variety of cargoes including various nanoparticulate pharmaceutical carriers (liposomes, micelles, microparticles, nanoparticles, polymer-conjugates). The conjugates comprise a detectable agent or a therapeutic agent, and the conjugates provide a novel strategy for site-specific delivery of the same to appropriate tissues in the subject. Versatile application of the conjugates in diagnostics and imaging is described.
