SHAHLA JAMZAD,JOHN P. CAESAR, JR.,MAJED FAWAZ,LAURA DAS,CHONG-HUI GU,PATRICIA NELL HURTER,MEGHAN M. JOHNSTON,ANDREW G. KUZMISSION,ELENI DOKOU,MEGHNA JAI ISRANI,DRAGUTIN KNEZIC,HONGREN WANG
申请号：
MX2014010253
公开号：
MX2014010253A
申请日:
2013.02.27
申请国别(地区):
MX
年份:
2014
代理人:
摘要：
The present invention relates to pharmaceutical compositions containing a solid dispersion of N- [2,4-Bis( 1,1 -dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-c arboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.La presente invención se refiere a composiciones farmacéuticas que contienen una dispersión sólida de N-[2,4-Bis(1,1-dimetilletil )-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida incluyendo formulaciones de dispersiones sólidas en polvos, gránulos y minicomprimidos, métodos para fabricar y procesar los polvos, gránulos y minicomprimidos, y métodos para tratar fibrosis quística empleando la composición farmacéutica.
