Spinnaker Biosciences, Inc.; Inc.;Massachusetts Institute of Technology;The Regents of the University of California;Spinnaker Biosciences
发明人:
Sailor, Michael J.,Kang, Jinyoung,Joo, Jinmyoung,Anglin, Emily,Kwon, Ester,Skalak, Matthew,Bhatia, Sangeeta
申请号：
AU2017250300
公开号：
AU2017250300A1
申请日:
2017.04.14
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Compositions useful in the controlled delivery of therapeutic agents and their methods of preparation and use are provided. The compositions comprise an optionally oxidized porous silicon core, a layer on the surface of the porous silicon core that comprises a metal silicate, and a therapeutic agent. The compositions optionally further comprise one or more targeting agents and/or cell-penetrating agents to enable the particles to target and enter cells or tissues of interest in a treated subject.
