THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
Martin D. BURKE,Stephen DAVIS
申请号:
US15541747
公开号:
US20180273571A1
申请日:
2016.01.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives and C16 carbamate derivatives of AmB. Also provided are methods of making the AmB derivatives.