Concise synthesis of urea derivatives of amphotericin B

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专利权人:

The Board of Trustees of the University of Illinois

发明人:

Burke, Martin D.,Davis, Stephen

申请号：

AU2016205187

公开号：

AU2016205187A1

申请日:

2016.01.08

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti -fungal activity. Certain of the derivatives are C16 urea derivatives and C16 carbamate derivatives of AmB. Also provided are methods of making the AmB derivatives.

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中国工程科技知识中心

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http://www.ckcest.cn/home/