David B. Weiner;Thanadavarayan Nagashunmugam;Velpandi Ayyavoo
发明人:
Velpandi Ayyavoo,Thanadavarayan Nagashunmugam,David B. Weiner
申请号：
US11639542
公开号：
US08183352B2
申请日:
2006.12.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to nucleic acid molecules encoding attenuated, non-functional virion infectivity factor (vif) proteins. The nucleic acid molecules of the invention are inserted into recombinant expression vectors and administered to mammals in order to induce a cellular and humoral immune response to the encoded protein product.
